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how to prevent job burnout

How To Prevent Job Burnout: Using The Allostatic Load Stress Calculator

How To Prevent Job Burnout: Using The Allostatic Load Stress Calculator Read More »

Did you know that safeguarding your well-being from job burnout can be simple using the Allostatic Load Calculator (ALI)? In today’s fast-paced work environment, chronic stress has become a pervasive issue, taking a toll on our physical and mental health. The ALI empowers individuals to assess the impact of stress on their bodies by studying the intricate interplay between inflammatory, neuroendocrine, and metabolic systems. At its core, allostatic load refers to the physiological consequences of chronic exposure to fluctuating or heightened neural or neuroendocrine responses, primarily arising from stress. To put it simply, it’s the wear and tear on our bodies due to chronic stress. Discover effective strategies on how to prevent job burnout through the assessment of allostatic load, gaining valuable insights into maintaining a healthy work-life balance and fostering resilience against the deleterious effects of chronic stress. Before delving into how the allostatic load calculator works, it’s essential to understand the broader concept of ‘allostasis.’ Unlike ‘homeostasis,’ which strives to maintain internal stability, allostasis pertains to the process by which the body adapts to stressors by establishing new norms. Essentially, it’s the body’s response to cope with stress at the expense of its natural norms, whether it’s a looming work deadline or a sudden scare. This article was last reviewed by Mai Saleh, Healsens, on January 22, 2023. This article was last modified on 21 January 22, 2023. Package of lab tests to calculate your allostatic load: IN THIS ARTICLE 1 For Whom is This Product Intended? 2 Study Your Allostatic Load to Understand How to Prevent Job Burnout 3 How to Prevent Job Burnout Unlocking Your Allostatic Load 4 Ordering Blood Tests RELATED ARTICLES For Whom is This Product Intended? If you engage in a high-stress job or face prolonged personal challenges without relief, this can result in chronic allostatic load. When such a load lasts for years, we can talk about the cumulative effect of allostatic load. It would not be an exaggeration to say that those with a high allostatic load are often at a greater risk of several health challenges, including: While stress is an inevitable part of life, its impact on our bodies doesn’t have to be. Just as understanding your biological age can inform lifestyle changes to reduce health risks, comprehending your allostatic load can guide interventions on how to prevent job burnout and address the associated challenges stemming from stress at home. This holistic approach addresses not only workplace stressors but also those encountered in personal life, ensuring a comprehensive strategy for maintaining overall well-being. As we delve into the significance of the Allostatic Load Calculator, we can appreciate its proactive approach to mitigating job burnout and other chronic stress, preserving long-term well-being. Study Your Allostatic Load to Understand How to Prevent Job Burnout Allostatic load cannot be directly observed because it is a latent and unobservable trait, but it’s possible to estimate it by summarizing data from a number of appropriate clinical biomarkers. The main reason is that it provides valuable information about your overall health status and can help identify areas for improvement. By undergoing an allostatic load blood test, you gain a comprehensive insight into the cumulative impact of stress on your body’s physiological systems. This not only enables early detection of potential health risks but also empowers you with the knowledge needed to proactively manage and optimize your well-being. In the quest to prevent job burnout, home measurements are as essential as blood test results. Assessing body composition with a measuring tape at home plays a crucial role in understanding your allostatic load. Monitoring changes in your body composition offers an accessible and practical method for tracking the physical effects of stress. From cardiovascular health to cognitive function, and now body composition, the results of these assessments collectively offer a roadmap for targeted interventions, guiding you towards a healthier, more resilient lifestyle. How to Prevent Job Burnout Unlocking Your Allostatic Load You can find out your allostatic load by taking blood tests, as well as taking some measurements of your body parameters. For residents of the Netherlands, the test package is available via the reference link above or through the Healsens app. Since the calculation requires not only blood tests but also measurements of body parameters, installing the Healsens app and ordering tests from it can be more convenient. Additionally, when ordering tests through the app, the results will be sent automatically. However, both options are equally effective. Ordering Blood Tests 1 Download the Healsens App from Google Play or the App Store, depending on your device. 2 Complete the registration process in the app. 3 Go to the “Risks” page via the bottom menu of the application. 4 Tap on the test you need — ”Allostatic Load Index (ALI)” 5 Tap on the “Add to Cart” button inside the test page and proceed with the ordering process. Process of taking blood tests in: Labplusarts ↗ Bloedwaardentest ↗ *For Residents of Other Countries: If you wish to assess your allostatic load but are not a resident of the Netherlands, Healsens cannot facilitate blood tests for you. However, you can take the necessary tests at any other laboratory in your country and input the obtained results into the application. Note If you order a blood test package through other labs, you need to manually enter the blood test results into the app. Because the app has no information about the person placing the order, this is necessary for the correct processing of the results. To receive the results directly in the app, install the app, choose the desired lab test package, and place the order directly from the app. When the order is placed from the app, the system recognizes your profile, and the results can be received automatically!

Biologische leeftijd berekenen

Biological Age Blood Test

Biological Age Blood Test Read More »

Did you know that you can determine your biological age through a simple blood test? While your chronological age is based on your date of birth, a biological age blood test measures various biomarkers to determine how well your body is aging. By taking this test, you can gain valuable insights into your overall health and identify areas where you may need to make lifestyle changes to improve your biological age. So, why should you care about your biological age? Well, research has shown that people with a higher biological age than their chronological age are at a greater risk for age-related diseases like heart disease, Alzheimer’s, and cancer. However, the good news is that you can take steps to reduce your biological age and lower your risk of these diseases. Package of lab tests to calculate biological age: IN THIS ARTICLE 1 For whom is this product intended? 2 Discover Your True Biological Age with a Blood Test: Why Should You Get Tested? 3 Why should you trust Healsens to calculate your biological age? RELATED ARTICLES For whom is this product intended? Biological age is a measure of an individual’s health and physical condition that goes beyond their chronological age. While we all age, the rate and manner of aging can differ significantly between individuals, based on lifestyle habits, genetics, and other factors. Measuring biological age can help individuals understand how their bodies are aging and identify areas for improvement in their health habits. One tool for measuring biological age is Levine’s Phenotypic Age calculator, which uses a combination of biological markers to estimate an individual’s age at the cellular level. So, for whom is this product? In short, anyone who is interested in their health and wants to take a proactive approach to aging. Individuals who want to optimize their health and longevity may benefit from using Levine’s Phenotypic Age calculator. This tool can be particularly useful for individuals who are at higher risk for age-related diseases, such as heart disease or cancer, or who have a family history of such conditions. Furthermore, individuals who have experienced significant changes in their lifestyle or health status may also benefit from measuring their biological age. For example, if someone has recently quit smoking, started exercising regularly, or made significant changes to their diet, measuring their biological age can provide an objective measure of the impact of these changes on their health. Discover Your True Biological Age with a Blood Test: Why Should You Get Tested? But why should you purchase lab tests to calculate your biological age? The main reason is that it provides valuable information about your overall health status and can help identify areas for improvement. By knowing your biological age, you can make informed decisions about your health and lifestyle, such as increasing physical activity, improving diet, or reducing stress levels. Moreover, measuring biological age can help you detect potential health issues early on when they are more manageable. For example, if someone’s biological age is significantly higher than their chronological age, it may indicate that they are at higher risk for age-related diseases, such as heart disease or cognitive decline. Armed with this knowledge, you can take proactive steps to reduce the risk and improve your overall health and well-being. In conclusion, measuring biological age using Levine’s Phenotypic Age calculator can provide individuals with valuable insights into their health and aging process. By understanding your biological age, you can take a proactive approach to your health and make informed decisions about your lifestyle habits. With this information, you can optimize their health and well-being and potentially increase their lifespan. » Explore everything about the significance of High Platelet Count results mean. How to Order Biological Age Blood Test? If you are interested in checking your biological age, you can easily purchase a blood test kit from Healsens. 1 Download the Healsens App from Google Play or the App Store, depending on your device. 2 Complete the registration process in the app. 3 Go to the “Risks” page via the bottom menu of the application. 4 Tap on the test you need — ”Levine’s Phenotypic Biological Age” 5 Tap on the “Add to Cart” button inside the test page and proceed with the ordering process. Process of taking blood tests in: Labplusarts ↗ Bloedwaardentest ↗ » Unlock Optimal Health: Discover How a Personalized Healsens General Check-up Plan Can Transform Your Well-being. Note If you want to assess your biological age but are not residing in the Netherlands or have opted for a different laboratory, Healsens cannot upload your blood test results for you. Nevertheless, you have the option to undergo the required tests at any laboratory in your country and manually input the obtained results into the application. Healsens will open more opportunities for you to naturally normalize your blood test results. Furthermore, you gain full access to investigate your health risk assessment based on the provided data. Why should you trust Healsens to calculate your biological age? Healsens is committed to providing you with accurate and reliable results that you can trust. We partner with Medical Laboratories Dr. Stein & Collegae, a highly respected and accredited laboratory in the Netherlands, to ensure that your blood samples are processed with the utmost care and accuracy. Lab Stein has an excellent reputation within the Dutch healthcare sector. With more than 20 medical specialists (laboratory doctors), chemists, biologists, doctors-microbiology etc. and 600 employees, the laboratory is one of the three largest medical laboratories in Europe. They carry out more than 5 million tests per year. Furthermore, we use Levine’s Phenotypic Age calculator to estimate your biological age. This algorithm has been proven with high accuracy in multiple studies and is widely accepted as a reliable method for calculating biological age. At Healsens, we understand that not everyone is comfortable with preventive medical examinations without a referral from their general practitioner. That’s why we work with our partners to ensure that our tests are conducted with the highest standards

Анализы крови в Нидерландах

Ordering Blood Tests Netherlands: A Comprehensive Guide

Ordering Blood Tests Netherlands: A Comprehensive Guide Read More »

Are you looking to get blood tests done in the Netherlands or undergo regular general health checkups? With the Healsens mobile app, residents of the Netherlands can now order blood tests without a referral from a general practitioner. This functionality enables you to obtain the essential tests you need, eliminating the need for a doctor’s visit. Simplify your healthcare journey with our blood test service in the Netherlands. RELATED ARTICLES 4 Receive Your Kit: A personalized test kit will be delivered to your provided home address. The test tubes will come equipped with a barcode linked to your research, and they will be specially prepared with liquid for shipment. It’s crucial to verify all your data to ensure accuracy. 5 Select a Test Center: Upon receiving a confirmation email, you’ll be prompted to choose a nearby blood test center where you can have your blood sample taken. It’s necessary to schedule an appointment and bring along your referral letter, test kit, and ID to the center. Trained professionals will collect the blood samples, ensuring that all tubes in your test kit are filled. 6 Send Your Kit: After your blood sample is collected, you’ll need to return the test kit to the lab using the prepaid packaging provided. Simply send the collection materials with the lab form as a letter, without registration or a track & trace code. Medical mail services in the Netherlands are highly efficient, ensuring the safe delivery of your samples to the laboratory. 7 Get Your Results: You will receive the results of your lab tests directly in the app (be sure to enable notifications to avoid missing results). Alternatively, you will receive your results via email. Most lab test results are typically available within a few days, up to a maximum of 10 working days. Your lab test results can be utilized to enhance your health through tailored advice on nutrition, supplements, and lifestyle changes. Healsens collaborates with various health coaches, specialists, and therapists who offer complementary care. The Healsens app grants access to personalized health plans, coaching, and support to assist you in achieving your health objectives. » Discover how to monitor and enhance your health with Healsens preventive checkup plan. How Healsens Saves Your Money* The application’s algorithm intelligently selects the most cost-effective lab test packs based on your chosen examinations, ensuring efficient use of your resources. If you prefer a customized examination plan, the algorithm also aids in identifying the most financially viable options for you. In the risk calculators section, you’ll also find the option to request a package of analyses for risk assessment. Here, you can conveniently order a package of analyses for DNAm PhenoAge or AIP calculator, among others. Why should you trust Healsens? Healsens is committed to providing you with accurate and reliable results that you can trust. We collaborate with Medical Laboratories Dr. Stein & College, a highly respected and accredited laboratory in the Netherlands, to ensure that your blood samples are processed with the utmost care and precision. Lab Stein has an excellent reputation within Dutch healthcare. With over 20 medical specialists (laboratory physicians), chemists, biologists, doctors in microbiology, and 600 employees, the laboratory is one of the three largest medical laboratories in Europe. They conduct more than 5 million tests annually. Availability: Our laboratory test package is cost-effective and utilizes affordable laboratory tests, making it accessible and user-friendly. At Healsens, we understand that not everyone feels comfortable with preventive medical examinations without a referral from their general practitioner. That’s why we work with our partners to ensure that our tests are conducted to the highest standards of care and confidentiality.

general check-up

Get a Personalized General Check-up: Your Key to Peace of Mind and Health

Get a Personalized General Check-up: Your Key to Peace of Mind and Health Read More »

Preventive medicine is rapidly advancing towards a more personalized approach. This shift, driven by international medical organizations, prioritizes disease prevention and tailors clinical recommendations to individual risk factors. However, many medical centers still offer a standard list of blood tests to all patients, overlooking these unique risk factors and updated guidelines. This generalized approach can delay the diagnosis of various diseases. It’s essential to know which specific blood tests should be part of your General Check-up to avoid missing potential illnesses. Moreover, understanding the appropriate tests can help you avoid unnecessary procedures, false diagnoses, and treatments, ultimately contributing to a sense of peace and well-being. Selecting a General Check-up that aligns with your personal health needs ensures you receive the most accurate and beneficial care. This article was last reviewed by Svetlana Baloban, Healsens, on January 24, 2022. This article was last modified on 3 March 2023. Screening vs. Diagnostic Tests When visiting a doctor, the tests you undergo can be classified into two categories: diagnostic and screening tests. Diagnostic tests are prescribed based on specific complaints to identify the underlying cause of symptoms. Screening tests, on the other hand, are recommended even in the absence of symptoms, aiming to detect diseases early based on age, sex, family history, or other risk factors. Personalized Screening with Healsens IN THIS ARTICLE 1 Screening vs. Diagnostic Tests 2 Personalized Screening with Healsens 3 Factors in General Check-up Decisions 4 Healsens General Check-up Plan RELATED ARTICLES Healsens adopts guidelines from reputable medical organizations like the US Preventive Services Task Force and the American Society of Clinical Oncology to personalize your General Check-up. By asking about your habits, weight, height, waist circumference, and more, Healsens considers individual risk factors to create a tailored preventive checkup plan. This ensures that your General Check-up is not only thorough but also relevant to your specific health needs. Factors in General Check-up Decisions Several factors determine the necessity and appropriateness of screening tests in a general check-up: Medical guidelines are continuously updated to reflect the latest research. Healsens leverages these guidelines to provide a list of necessary tests based on your individual risk factors, including: Interesting Fact Do you know that there are several methods for testing mutations in the BRCA1 and BRCA2 genes? The most accessible and inexpensive one is PCR testing for mutations in the BRCA1 and BRCA2 genes. And as you might guess, it is the least accurate. Only 5% of all cases of mutations will be diagnosed by this testing method. Therefore, if you have a family history of breast or ovarian cancer, the NGS method is used as a screening method. Healsens General Check-up Plan The Healsens General Check-up plan offers a comprehensive and personalized approach to preventive health maintenance. By incorporating the latest medical guidelines and research, Healsens ensures you receive the most appropriate screening tests for your unique health needs. This proactive approach not only enhances early detection and prevention of potentially life-threatening illnesses but also brings a sense of peace and well-being. Healsens’ personalized General Check-up plan considers your individual risk factors, leveraging up-to-date guidelines to offer a tailored, comprehensive health screening. This approach helps you stay ahead of potential health issues while avoiding unnecessary interventions, ensuring your peace of mind and optimal health.

Biologische leeftijd berekenen

Biological Age By Dnam Phenoage

Biological Age By Dnam Phenoage Read More »

Aging is an inevitable process, but there are differences in susceptibility to age-related diseases and the risk of death among people of the same chronological age. This means that different people have differences in the rates of biological aging. To better understand the differences between biological and chronological age, it is necessary to measure biological aging. For this purpose, various calculators of biological age have been developed, which allow us to assess the impact of lifestyle on the aging process. One such biomarker is DNAm PhenoAge, a biological age biomarker developed at Yale University. DNAm PhenoAge significantly outperforms previous measurements in predicting various aging outcomes, including all-cause mortality, cancer, health span, physical functioning, and Alzheimer’s disease. This article was last reviewed by Svetlana Baloban, Healsens, on March 4, 2023. This article was last modified on 28 February 2023. What is Biological Age by DNAm PhenoAge? DNAm PhenoAge is an aging biomarker developed at Yale University that measures a person’s biological age. It is based on data from NHANES III and includes 9 biomarkers, such as the number of red and white blood cells, as well as a person’s chronological age. It is capable of predicting risks of various aging outcomes in tissues and cells and provides insight into important pathways of aging. The DNAm PhenoAge biomarker has been validated in NHANES IV as a strong predictor of morbidity and mortality risk, and has been tested for accuracy in calculations on several patient cohorts taking into account age-related outcomes. So, the biological age according to DNAm PhenoAge is a fairly accurate predictor of healthspan and lifespan at the epigenetic level. This means that biological age according to DNAm PhenoAge can be used as an indicator of a person’s health status before any pathologies appear. For most people, this can be a good indicator of the real state of their health before they encounter any diagnoses. IN THIS ARTICLE 1 What is Biological Age by DNAm PhenoAge? 2 How to use biological age calculator? 3 Is it possible to reverse biological aging? RELATED ARTICLES How to determine your biological age? To calculate biological age using DNAm PhenoAge, several simple blood tests need to be taken, including: Biological Age Blood Test Units Albumin ↑ Liver g/L Creatinine ↓ Kidney umol/L Glucose, serum ↓ Metabolic mmol/L C-reactive protein ↓ Inflammation mg/dL Lymphocyte percent ↑ Immune % Mean cell volume (MCV) ↓ Immune fL Red cell distribution width (RDW) ↓ Immune % Alkaline phosphatase ↓ Liver U/L White blood cell count (WBC) ↓ Immune 1000 cells/uL Age Years Table 1. Phenotypic aging measures In general, the DNAm PhenoAge biomarker can be determined through inexpensive blood tests, making it accessible to most people. After receiving the test results, online calculators can be used to calculate one’s biological age based on DNAm PhenoAge. This is convenient not only for a one-time calculation but also for monitoring the dynamics of biological age over time. Below you can see the biomarkers of our user who, over the course of several years, was able to reduce their biological age by 21 years compared to his chronological age with the help of changes in their diet and physical activity. Albumin Creatinine Glucose hs C-react Protein Lymphs (Lympocyte, % not absolute) MCV (Mean Cell Volume) RDW (Red Cell Dist Width) or Red Blood Cell Distribution Width (RDW-SD)? Alkaline Phosphatase WBC (White Blood Cells) Age ↑ ↓ ↓ ↓ ↑ ↓ ↓ ↓ ↓ 49 60.000 4.6 0.3 43.2 90 11.8 40 4.2 49.1 g/L umol/L mmol/L Ln(mg/L) % fL % U/L 10^3 cells/uL years Table 2. Lab test results of a 49-year-old man whose biological age is 21 years less than his chronological age. How to use biological age calculator? The calculated biological age by Levine’s DNAm PhenoAge is compared to the current chronological age. If the result is lower than your passport age, it is not only good news but also an indicator that your lifestyle positively affects your health. But what if the situation is the opposite? The most important thing is not to get upset! Now you know that you should pay attention to your health, and it makes sense to review your lifestyle. Thanks to the fact that there are several biomarkers, you can see what exactly to focus on. In addition, by making changes to your lifestyle, you can evaluate each individual indicator in addition to your biological age. To understand whether the dynamics are positive for each indicator, let’s return to Table 1. Each biomarker contains arrows ↓ or ↑. These arrows indicate a positive trend. For example, the downward arrow “↓” next to the glucose level indicates that lower levels of glucose indicate a younger biological age. Is it possible to reverse biological aging? New research shows that we can actually reverse biological aging through diet and lifestyle. In 2021, it was published the results of a pilot randomized clinical trial that demonstrated the ability to reverse biological age and was confirmed by objective outcomes. This is a very interesting observation, and there are several factors that can influence biological aging. Our lifestyle, comprising factors such as diet, physical activity, and stress, is considered a crucial element that affects biological age. In an effort to reverse the biological age in humans, researchers utilized a combination of diet, physical activity, and stress resilience techniques. The study monitored a group of individuals who were enrolled in a health program featuring a balanced low-calorie diet, daily 30-minute exercise at 60-80 percent intensity of maximum perceived exertion, and breathing exercises twice a day. Additionally, the study also focused on the quality of sleep, and it was discovered that insomnia was linked to an increase in DNAmAge clocks. Another study also found a connection between poor sleep quality/less sleep hours and accelerated aging in a small sample of 12 college female students. In the end, those who adhered to the recommended health program showed a reduction in age by 9 years, indicating that by maintaining a balanced diet, regular physical activity, and effective stress management,

Соотношение кортизол/ДГЭА-С

Cortisol/Dhea-S Ratio Of Longevity

Cortisol/Dhea-S Ratio Of Longevity Read More »

A complex interaction between cortisol and dehydroepiandrosterone-sulphate (DHEA-S) is crucial in the stress system balance. In particular, significantly higher or lower cortisol/DHEA(S) ratios have been associated with depression and aggression. In general, DHEA-S levels affect various body systems, as well as prevent aging (Chahal and Drake 2007). That is why the Cortisol DHEA ratio is a very informational indicator, which, along with other indicators calculated in Healsens, provides important information about human health. Thus, using the ratio of cortisol / DHEA-S, you can assess body responses to exercise or evaluate mental health. Another benefit is that you can check your cortisol and DHEA-S levels at home. This article was last reviewed by Svetlana Baloban, Healsens, on January 24, 2020. This article was last modified on 4 March 2021. How Cortisol and DHEA Sulfate Affect the Body Let’s start by looking at how cortisol and DHEA-S affect overall health. Dehydroepiandrosterone (DHEA) and cortisol are produced in the adrenal glands and are both derived from pregnenolone. So, DHEA and DHEA-S production reaches its peak at the age of 20–30 and then declines progressively with age. When it comes to cortisol levels, while some studies show that cortisol increases with age, others do not support this observation. However, everyone agrees that the reduction in DHEA-S entails disruption of various physiological systems. Stress Level As mentioned above, DHEA and DHEA-S play a protective role during acute stress as an antagonist to the action of the stress hormone cortisol. In turn, cortisol also helps to effectively manage stress. Let’s see how this happens. About 15 minutes after a stressful situation, cortisol levels rise and remain elevated for several hours. This marks the onset of stage 1. During this stage, there are elevations in cortisol with no corresponding changes in DHEA. Subsequently, glucose is mobilized, non-essential organ systems are suppressed, and inflammation is reduced. All of these physiological responses collectively enable the body to effectively cope with stress. However, in cases of chronic stress, this adaptive reaction can take a catastrophic turn: cortisol loses its ability to function normally. This transition ushers in stage 2. In this latter stage, the persistence of stress leads to a sustained peak in cortisol levels, matched by a corresponding elevation of DHEA. IN THIS ARTICLE 1 How Cortisol and DHEA Sulfate Affect the Body 2 Assessing Exercises 3 Adrenal/DHEA Restoration RELATED ARTICLES It becomes increasingly challenging to maintain appropriate blood sugar levels, to allow for adequate rest, to achieve high-quality sleep, and to achieve a harmonious balance among other hormones. This signals the arrival of stage 3, wherein stress persists and becomes chronic. During this stage, cortisol levels decrease, while DHEA remains elevated. In the absence of timely intervention, prolonged adrenal hyperstimulation can result in adrenal exhaustion. This condition is eventually manifested by a decline in both cortisol and DHEA, a phase often denoted as adrenal exhaustion or stage 4. Ultimately, this process may culminate in adrenal failure. Thus, the optimal ratio between salivary cortisol and DHEA is approximately 5:1 to 6:1, serving as an indicator of a normal state of adaptation to stress. When the body’s ability to maintain its normal stress adaptation is compromised, a process known as stress maladjustment can ensue. This phenomenon is now recognized as a chronic stress response, often identified by terms like pregnenolone steal, cortisol escape, or an elevated cortisol to DHEA ratio. The longer one remains in a state of chronic stress, the more pervasive its negative impact becomes on various aspects of physical well-being. As a result, individuals grappling with depression or heightened anxiety levels (measured at 0.24 ± 0.03 in the healthy group compared to 0.41 ± 0.12 in the group of individuals with severe anxiety), along with those dealing with post-traumatic stress disorder, exhibit disruptions in the cortisol to DHEA ratio. Nevertheless, it’s worth noting that certain studies have demonstrated the potential of DHEA treatment to mitigate the adverse health effects associated with stress. Musculoskeletal disorders We have already mentioned that cortisol dysfunction entails disorders of the musculoskeletal system. Thus, the higher the cortisol / DHEA-S ratio, the more serious the risk of this problem. Moreover, multiple regression analysis showed that the independent risk factor for sarcopenia was a serum cortisol/DHEA-S ratio ≥ 0.2. Sarcopenia is a type of muscle loss that occurs with aging and/or immobility. Immunity and Cortisol DHEA Ratio In addition, an increase in the cortisol / DHEA-S ratio with age (Phillips et al. 2007) is associated with immune dysfunction and the risk of infection in the elderly due to the fact that DHEA-S enhances immunity. However, cortisol has an inverse immunosuppressive effect (Buford and Willoughby 2005). It is also worth adding that DHEA-S is known for its antioxidant properties. Metabolic Syndrome Various studies have shown that both cortisol and DHEAS are related to metabolic syndrome, and type 2 diabetes. While high cortisol concentrations are associated with an increased risk of metabolic syndrome, high DHEA-S levels appear to be protective. By far, the strongest associations were observed for the cortisol / DHEA-S ratio. According to observations, the higher the coefficient, the greater the risk of metabolic syndrome. This ratio is also strongly associated with four of the five components of metabolic syndrome. Alzheimer’s Disease The cortisol / DHEA-S ratio may also be crucial in Alzheimer’s disease. For example, some studies have found a link between the cortisol / DHEA-C ratio and a decrease in hippocampal volume. It is worth saying that a decrease in the volume of the hippocampus is one of the early diagnostic signs of Alzheimer’s disease. This finding has been confirmed by other studies, observing the relationship between cortisol / DHEA-S and hippocampal atrophy (HA). For example, such a direct relationship was observed in patients with Cushing’s syndrome. Moreover, HC volume partially recovered following treatment-induced cortisol decrease. However, not all studies support this association within normal cortisol levels in healthy people. To sum up, the ratio of cortisol / DHEA sulfate can reflect: Assessing Exercises DHEA (Aldred et al. 2009; Cumming et al. 1986) and DHEA-S (Tremblay et al.

cardiovascular risk assessment

CARDIOVASCULAR RISK ASSESSMENT

CARDIOVASCULAR RISK ASSESSMENT Read More »

Cardiovascular diseases such as ischemic heart disease, thrombosis, arterial hypertension with its complications – myocardial infarction and stroke – constitute a dynamic multistep process that is closely related to inflammation. It is well-known that CVD diseases rank first among all other diseases of mankind. Traditionally for making an accurate diagnosis, the patient must undergo a series of procedures, undergo lab tests so that the doctor can prescribe the necessary treatment. However, there is another way. Doctors can use cardiovascular risk assessment tools aimed at detecting the disease at an early stage. This time, not only will we consider different methods / risk calculators that are now used in clinical practice, but we will also make the corresponding calculations using a real example of a patient’s history. And, of course, let’s talk about why, given the presence of such intelligent systems, the CVD problem is still relevant. This article was last reviewed by Svetlana Baloban, Healsens, on January 24, 2020. This article was last modified on December 15, 2020. Why do you need cardiovascular risk assessments? Before proceeding to describe various calculation methods, let’s find out why they are needed at all. To begin with, we shall that most heart diseases develop completely asymptomatically over many years. In practice, it means that if one doesn’t feel any health problems, he or she simply does not go to the doctor unless a critical condition occurs. So, according to some estimates, 3.7 million Americans remain with undiagnosed heart disease. At the same time, the highest proportion of undiagnosed CVDs, which led to death from cardiovascular diseases, is among people aged 18–59 years. This is especially true when you consider that obesity, type 2 diabetes, and other risk factors are becoming more common at a young age. Second, understanding the risks allows for early diagnosis of CVD and, accordingly, preventive lifestyle interventions or treatment as needed. And thirdly, the assessment of risk factors can clearly demonstrate how the total risk changes if you switch to a healthier lifestyle. That is why, as early as in 1948, the Framingham Heart Study was initiated under the direction of the US National Heart, Lung, and Blood Institute. It was an ambitious medical research project that changed the medicine we know. As part of this study, the main risk factors for cardiovascular disease were identified. These include the following indicators: IN THIS ARTICLE 1 Why do you need cardiovascular risk assessments? 2 SCORE Risk Chart (Systematic Coronary Risk Evaluation) 3 Framingham Risk Score 4 Reynolds Risk Score 5 ASCVD (Atherosclerotic Cardiovascular Disease) Risk Score 6 PROCAM Score (Prospective Cardiovascular Munster Study) 7 QRISK (QRESEARCH Cardiovascular Risk Algorithm) 8 The 65yo Patient’s CVD Risks 9 Effectiveness of Using CVD Risk Scoring RELATED ARTICLES Valuable information has also been obtained on the role of cholesterol, age, gender, and psychological problems. During this time, the risk assessment has changed and developed significantly. In this article, we will analyze what cardiovascular risk assessment means and what calculators are used now in medical practice. SCORE Risk Chart (Systematic Coronary Risk Evaluation) The European guidelines for cardiovascular disease (CVD) prevention recommend the use of modified SCORE risk charts. SCORE estimates the 10-year risk of fatal and non-fatal CVDs such as myocardial infarction, cerebrovascular disease, and congestive heart failure. The first Joint Working Group of European societies on coronary prevention used a simple risk chart. For their calculations, they considered the following categories: Then, the diagram became more complex in order to assess risks more accurately. So, in addition to total cholesterol, the ratio of cholesterol to HDL cholesterol was also taken into account in risk assessments. In addition, given the geographic variability in cardiovascular risk across Europe, two SCORE charts have been developed for countries with high and low CVD risk. Countries with low risk include countries such as Andorra, Austria, Belgium, Cyprus, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Israel, Italy, Luxembourg, Malta, Monaco, Netherlands, Norway, Portugal, San Marino , Slovenia, Spain, Sweden, Switzerland and the United Kingdom of Great Britain and Northern Ireland. Countries at high risk of CVD: Bosnia and Herzegovina, Croatia, Czech Republic, Estonia, Hungary, Lithuania, Montenegro, Morocco, Poland, Romania, Serbia, Slovakia, Tunisia and Turkey. And the group of countries with a very high risk (note that the diagrams may underestimate the risk in these countries) included such countries as: Albania, Algeria, Armenia, Azerbaijan, Belarus, Bulgaria, Egypt, Georgia, Kazakhstan, Kyrgyzstan, Latvia, North Macedonia , Moldova, Russian Federation, Syrian Arab Republic, Tajikistan, Turkmenistan, Ukraine and Uzbekistan. Due to this SCORE scale, the following cardiovascular diseases can be detected: stroke, myocardial infarction, pulmonary embolism, dissecting aortic aneurysm. Framingham Risk Score The Framingham Risk Scale (FRS) determines the presence of diseases such as angina pectoris, coronary heart disease, myocardial infarction, stroke. Like the SCORE scale, this system opens the door for making a forecast for the next 10 years. This scale was developed in North America. Thus, NCEP 4 recommends the Framingham Risk Score for cardiovascular risk assessment. You can also calculate it by yourself. The total risk on the Framingham scale is defined as: A value over 30% indicates a very high risk of cardiovascular disease. A 10-year risk estimate can be obtained as a percentage, which is then used to make decisions about disease prevention. This assessment is also evolving. For example, in 2009 CCS added additional risks to the Framingham risk scale. It included a family history of coronary heart disease in a first-line relative. It takes into account male first-degree relative younger than 55 years and female first-degree relative younger than 65 years old. For elderly patients, sensitive C-reactive protein results can also help to reclassify risks. Reynolds Risk Score If you are healthy and do not have diabetes, the Reynolds Risk Score is designed for your cardiovascular risk assessment. It may predict your risk of heart attack, stroke, or other serious heart diseases over the next 10 years. The risk calculation is designed for people aged 45 and over. The scale assesses the following risk factors: gender, age, systolic blood pressure, total and

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HEALSENS SMART MOBILE HEALTH APP

HEALSENS SMART MOBILE HEALTH APP Read More »

Often, we encounter difficulties in obtaining a comprehensive medical history from hospitals – including analyses, imaging, and treatment information. Electronic health records, prevalent worldwide, often prove ineffective for patients due to data management complexities and the presentation of research findings in conventional lab reports. Recently, new solutions have emerged that provide patients with not only data but also valuable resources. However, given access to such a volume of patient data, why not analyze it? Research conducted by various physicians using diverse calculators and algorithms on electronic health records can significantly benefit patient health preservation. Let’s take a look at the example of the Healsens electronic health record – how it processes patient data to calculate health risks and the functionalities employed to achieve these objectives within the context of mobile health apps. Healsens is designed to gather preventive medicine outcomes and implement them into personalized recommendations. One of its key objectives is assessing health risks, validating them through medical research, and providing preventive care. For individuals, this means having a solution at their fingertips capable of aiding in disease prevention. For physicians, it involves evaluating the risks faced by their patients. Let’s explore together the tools utilized by Healsens: risk calculators, screening plans, analysis of biometric data, tracking medical history, and lifestyle change recommendations. These components collectively elucidate how Healsens operates. Health Plan and Health Screenings The foundation of a preventive approach relies on two main pillars – health screenings and health risk assessments. Your health plan serves as your guide, continually adapting to changes occurring within your body. The main screen of Healsens immediately presents your personalized health plan, unique to each individual. It, much like you, evolves to track changes and respond promptly. If you’re young and healthy, your plan will be concise. As you age, it expands, considering potential bodily changes. Initiated your plan? Explore its contents. Here, blood tests, at-home parameter measurements, health screenings, and questionnaires provide a comprehensive health assessment. Blood tests offer insights into your body, while questionnaires gauge your emotional well-being. These tools are recommended for self-diagnosis. For each examination, whether blood tests, MRI, CT scans, or ultrasound, you’ll discover: IN THIS ARTICLE 1 Health Plan and Health Screenings 2 Assessing your health condition and disease development risks 3 Storage and Analysis of Data in Healsens Electronic Cards 4 Health Screening Sources 5 Surveys 6 Monitoring Well-being and Health Diaries RELATED ARTICLES Upon the initial creation of the plan, it takes into account your age and gender, assuming your overall health. However, as new data becomes available, the plan becomes more personalized. Depending on changes, various analyses or health screenings may be suggested to you, and the app will notify you about the reasons for these changes. The more diverse health factors are known, the better the electronic health record can tailor an individual screening list to maximize health preservation. This encapsulates the essence of a smart electronic medical record and the Healsens mobile app. Preventive medicine is increasingly becoming personalized, hence some screenings are recommended specifically for individuals in at-risk categories. Thus, some screenings may be proposed to you only after an assessment of health risks. It’s worth noting that such a personalized approach not only saves money but also aids in better health issue diagnosis. Consider the facts: according to survey data, in 2018, over 65% of Europeans visited a doctor for preventive check-ups and tests. However, only 17% included age-related screenings, which are a primary cause of early mortality and disability worldwide. Assessing your health condition and disease development risks Assessing health status and risk calculators are the second crucial aspect in maintaining health. Numerous organizations develop their risk calculators, curate lists of risk factors, and collaborate with scientific entities to identify individuals at risk. The primary goal is disease prevention. It’s important to note that most chronic conditions are more effectively treated at early stages, making treatment more efficient, accessible, and usually resulting in fewer complications. For instance, prediabetes is considered a reversible condition, while unfortunately, diabetes remains incurable. Within the Healsens app, the risk assessment process is complemented by a unique approach. Risk calculators, found in the “Risks” section, integrate data from your health plan, considering analysis results and other parameters. As you progress through the health plan, you automatically assess your risks. However, these calculators also consider the user’s profile, displaying only relevant risks. Examples of such individualized approaches can vary. For instance, the cardiovascular risk calculator SCORE 2 is not optimal for individuals under 40 and is specifically designed for European continent residents. This specificity is detailed in the article “Assessment of Cardiovascular Risk.” Users under 40 or residing outside the SCORE 2 assessment zone will not see this calculator. Storage and Analysis of Data in Healsens Electronic Cards Mobile Health Apps: Healsens The Healsens mobile app for electronic medical cards stands out as an exemplary suite of mobile health apps, enabling users to upload and monitor their own medical data. It isn’t tied to a specific clinic, doctor, or country, offering versatility for users globally. The card system is user-friendly: individuals from any part of the world can input their data, tailor it to their needs, and then track its dynamics. However, this approach comes with one drawback: the necessity for manual input of results. Yet, for some countries, medical history synchronizes automatically, which is undoubtedly convenient. Every laboratory test and medical examination represented in numerical format can be visualized as graphs. In addition to standard values provided by laboratories, users have the option to set personal targets to assess the effectiveness of treatment and the pace of achieving optimal indicators. Within the app, laboratory references and user-set targets are displayed as two distinct entities. Why is this so? Laboratories establish reference values, considering, among other factors, the accuracy of their equipment. This leads to different reference values set by different labs, accounting for their individual margins of error. It makes sense to preserve these ranges. The set targets for analyses in Healsens represent

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