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Complete blood count (CBC) + Leuco Diff and RDW·
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high platelet count

What Does A High Platelet Count Mean

What Does A High Platelet Count Mean Read More »

Platelets, or thrombocytes, are crucial blood components produced in the bone marrow, play a pivotal role in blood clotting and serve as vital inflammatory and immune mediators. When platelets become activated and aggregate, their size, measured during a blood test, can also increase. This phenomenon, known as a high platelet count, can sometimes elevate the risk of cardiovascular issues. Patients who had an elevated above normal platelet count in the general blood test had a greater risk that they would have a malignant neoplasm (lung cancer or colorectal cancer) within the next year. The risk was especially increased if thrombocytosis was detected at least twice in 6 months. Hence, maintaining platelet count and Mean Platelet Volume (MPV) within optimal ranges is paramount. So, what does it signify when a routine blood analysis reveals an elevation in platelet levels? What are the symptoms? What symptoms might you experience? For many people with thrombocythemia or thrombocytosis, there may be no noticeable symptoms, and these conditions may only be detected through routine blood tests. However, if you do experience symptoms due to a high platelet count, they are typically associated with either blood clots or bleeding. These symptoms are more prevalent among individuals with thrombocythemia. In cases of thrombocythemia, blood clots commonly form in the brain, hands, and feet, though they can occur anywhere in the body. Blood clots in the brain might result in chronic headaches and dizziness. In severe instances, you might even experience a transient ischemic attack or a stroke. Blood clots may also develop in the small blood vessels of the hands and feet, leading to numbness and redness in these areas. You might feel a burning sensation and throbbing pain, especially in the palms of your hands and the soles of your feet. IN THIS ARTICLE 1 What are the symptoms? 2 What can lead to a high platelet count? 3 Primary thrombocytosis 4 Natural ways to lower high platelet count RELATED ARTICLES Additional symptoms of a blood clot include confusion or changes in speech, migraines, seizures, discomfort in the upper body (such as in one or both arms, back, neck, jaw, or abdomen), shortness of breath coupled with nausea, weakness, chest pain, and complications during pregnancy. Additionally, an enlarged spleen could also be present. Factors that may increase your risk of developing a blood clot include older age, a history of previous blooDiscover Blood Test Insights in Healsens Appd clots, smoking, and other underlying health conditions such as diabetes and high blood pressure. What can lead to a high platelet count? Let’s start with the fact that you shouldn’t have a complete blood count test while fasting or on a fasting-mimicking diet. You should wait 7 days after fasting. Otherwise, platelet levels during fasting and immediately afterward will be very high. Additionally, an increase in platelet levels can also be a response to stress, injury, or physical activity. Moreover, high platelet levels can be caused by another condition or the use of certain medications. This is called secondary thrombocytosis and accounts for 80% to 90% of cases of elevated plateletsх. The list of reasons that can cause an increase in platelets includes: In such cases, platelet levels will return to normal after treating the underlying condition. For example, normalization of platelet counts can be achieved by taking iron supplements in patients with inflammatory bowel disease. Treatment of thrombocytosis with aspirin is generally not recommended. » Discover everything about what your cholesterol results mean. Primary thrombocytosis However, elevated levels of platelets can be caused by a disruption in platelet production by bone marrow precursor cells. This condition is known as primary thrombocytosis. Typically, for individuals at low risk—those who are younger (up to 60 years old) and have no history of thrombosis—treatment with aspirin is recommended if there are no serious contraindications to taking aspirin. Platelets have a lifespan of 7-10 days. After taking an aspirin tablet, platelets lose their ability to aggregate and form clots for the entire duration of their existence—around 7-10 days. For individuals at high risk—typically older individuals (over 60 years old) with a history of previous thrombosis—the preferred options are antiplatelet therapy (low-dose aspirin) and cytoreductive therapy. Natural ways to lower high platelet count Several clinical trials have shown that tomatoes, cocoa, grapes, kiwi, and ginkgo have an inhibitory effect on platelet aggregation. The polyphenols in these plants can influence the cardiovascular system by reducing blood pressure, improving endothelial function, enhancing antioxidant protection, inhibiting the oxidation of low-density lipoproteins, and reducing inflammatory reactions. Flaxseed (Linum usitatissimum), sea buckthorn berries (Hippophae), and argan oil (Argania spinose) may also be beneficial in appropriate doses. It should be noted that garlic and ginkgo may enhance the pharmacological action of aspirin. Therefore, caution should be exercised when using garlic/ginkgo concurrently with aspirin. Ordering Blood Tests in the Netherlands If you are interested in checking your platelet count level, you can easily purchase a blood test kit from Healsens. 1 Download the Healsens app from Google Play or the App Store, depending on your device. 2 Complete the registration process in the app. 3 Tap on ”Order Blood Tests”. 4 Find the Complete blood count (CBC) test and tap on the “Add to Cart” button. Proceed with the ordering process. » Unlock Optimal Health: Discover How a Personalized Healsens General Check-up Plan Can Transform Your Well-being. Note If you want to assess your platelet count level but are not residing in the Netherlands or have opted for a different laboratory, Healsens cannot upload your blood test results for you. Nevertheless, you have the option to undergo the required tests at any laboratory in your country and manually input the obtained results into the application. Healsens will open more opportunities for you to naturally normalize your blood test results. Furthermore, you gain full access to investigate your health risk assessment based on the provided data.

how to prevent job burnout

How To Prevent Job Burnout: Using The Allostatic Load Stress Calculator

How To Prevent Job Burnout: Using The Allostatic Load Stress Calculator Read More »

Did you know that safeguarding your well-being from job burnout can be simple using the Allostatic Load Calculator (ALI)? In today’s fast-paced work environment, chronic stress has become a pervasive issue, taking a toll on our physical and mental health. The ALI empowers individuals to assess the impact of stress on their bodies by studying the intricate interplay between inflammatory, neuroendocrine, and metabolic systems. At its core, allostatic load refers to the physiological consequences of chronic exposure to fluctuating or heightened neural or neuroendocrine responses, primarily arising from stress. To put it simply, it’s the wear and tear on our bodies due to chronic stress. Discover effective strategies on how to prevent job burnout through the assessment of allostatic load, gaining valuable insights into maintaining a healthy work-life balance and fostering resilience against the deleterious effects of chronic stress. Before delving into how the allostatic load calculator works, it’s essential to understand the broader concept of ‘allostasis.’ Unlike ‘homeostasis,’ which strives to maintain internal stability, allostasis pertains to the process by which the body adapts to stressors by establishing new norms. Essentially, it’s the body’s response to cope with stress at the expense of its natural norms, whether it’s a looming work deadline or a sudden scare. This article was last reviewed by Mai Saleh, Healsens, on January 22, 2023. This article was last modified on 21 January 22, 2023. Package of lab tests to calculate your allostatic load: IN THIS ARTICLE 1 For Whom is This Product Intended? 2 Study Your Allostatic Load to Understand How to Prevent Job Burnout 3 How to Prevent Job Burnout Unlocking Your Allostatic Load 4 Ordering Blood Tests RELATED ARTICLES For Whom is This Product Intended? If you engage in a high-stress job or face prolonged personal challenges without relief, this can result in chronic allostatic load. When such a load lasts for years, we can talk about the cumulative effect of allostatic load. It would not be an exaggeration to say that those with a high allostatic load are often at a greater risk of several health challenges, including: While stress is an inevitable part of life, its impact on our bodies doesn’t have to be. Just as understanding your biological age can inform lifestyle changes to reduce health risks, comprehending your allostatic load can guide interventions on how to prevent job burnout and address the associated challenges stemming from stress at home. This holistic approach addresses not only workplace stressors but also those encountered in personal life, ensuring a comprehensive strategy for maintaining overall well-being. As we delve into the significance of the Allostatic Load Calculator, we can appreciate its proactive approach to mitigating job burnout and other chronic stress, preserving long-term well-being. Study Your Allostatic Load to Understand How to Prevent Job Burnout Allostatic load cannot be directly observed because it is a latent and unobservable trait, but it’s possible to estimate it by summarizing data from a number of appropriate clinical biomarkers. The main reason is that it provides valuable information about your overall health status and can help identify areas for improvement. By undergoing an allostatic load blood test, you gain a comprehensive insight into the cumulative impact of stress on your body’s physiological systems. This not only enables early detection of potential health risks but also empowers you with the knowledge needed to proactively manage and optimize your well-being. In the quest to prevent job burnout, home measurements are as essential as blood test results. Assessing body composition with a measuring tape at home plays a crucial role in understanding your allostatic load. Monitoring changes in your body composition offers an accessible and practical method for tracking the physical effects of stress. From cardiovascular health to cognitive function, and now body composition, the results of these assessments collectively offer a roadmap for targeted interventions, guiding you towards a healthier, more resilient lifestyle. How to Prevent Job Burnout Unlocking Your Allostatic Load You can find out your allostatic load by taking blood tests, as well as taking some measurements of your body parameters. For residents of the Netherlands, the test package is available via the reference link above or through the Healsens app. Since the calculation requires not only blood tests but also measurements of body parameters, installing the Healsens app and ordering tests from it can be more convenient. Additionally, when ordering tests through the app, the results will be sent automatically. However, both options are equally effective. Ordering Blood Tests 1 Download the Healsens App from Google Play or the App Store, depending on your device. 2 Complete the registration process in the app. 3 Go to the “Risks” page via the bottom menu of the application. 4 Tap on the test you need — ”Allostatic Load Index (ALI)” 5 Tap on the “Add to Cart” button inside the test page and proceed with the ordering process. Process of taking blood tests in: Labplusarts ↗ Bloedwaardentest ↗ *For Residents of Other Countries: If you wish to assess your allostatic load but are not a resident of the Netherlands, Healsens cannot facilitate blood tests for you. However, you can take the necessary tests at any other laboratory in your country and input the obtained results into the application. Note If you order a blood test package through other labs, you need to manually enter the blood test results into the app. Because the app has no information about the person placing the order, this is necessary for the correct processing of the results. To receive the results directly in the app, install the app, choose the desired lab test package, and place the order directly from the app. When the order is placed from the app, the system recognizes your profile, and the results can be received automatically!

simple sleep diary

Unlocking Better Sleep: The Power Of A Simple Sleep Diary

Unlocking Better Sleep: The Power Of A Simple Sleep Diary Read More »

Insomnia is a common condition characterized by significant disruptions in functions and quality of life and can lead to mental and physical health issues. The main symptoms of insomnia include difficulty falling and staying asleep, along with frequent discomfort and impairment of daytime functioning. This condition affects about 10% of the population. If you’re experiencing insomnia, it’s important to know where to seek help and how to address this problem. Additionally, a useful tool is a simple sleep diary, which can be highly effective in managing this issue. This article is undergoing validation. The latest changes were made on November 20, 2023. How Does Insomnia Affect Health? In the vast majority of cases, insomnia is linked to mental or somatic illnesses. Insomnia can have a significant impact on our lives. In fact, it’s a risk factor for developing depression, anxiety disorders, substance use disorders, suicidal behavior, hypertension, and diabetes. When we suffer from sleepless nights, it reflects in our daytime well-being. We experience fatigue as if our energy has depleted in the morning, hindering our ability to function properly. Attention and concentration decline, disrupting our ability to focus on work, studies, or interactions. If you’re facing this issue, the Epworth Sleepiness Scale is widely used in the sleep medicine field as a subjective measure of sleepiness. This scale helps determine if you’re experiencing excessive sleepiness that requires medical attention. But wait, there’s more! Sleepless nights sometimes lead to mood changes. We become irritable, or perhaps even sad, making communication difficult and impacting our social and family life. Professional or academic tasks start to feel overwhelming because we simply can’t focus or retain necessary information. IN THIS ARTICLE 1 How Does Insomnia Affect Health? 2 Diagnosing Insomnia 3 Current Sleep History 4 Sleep Diary 5 How to Utilize a Simple Sleep Diary? RELATED ARTICLES The Role of a Simple Sleep Diary A simple sleep diary can be an invaluable tool in understanding sleep patterns, recording sleep disruptions, and identifying potential triggers. It aids in tracking the quantity and quality of sleep, helping healthcare providers comprehend the severity of the issue and guide effective treatment strategies. Insomnia isn’t merely a disturbance in nightly rest; it’s a complex condition that affects mental, physical, and social aspects of life. Utilizing a simple sleep diary, along with seeking professional guidance, can be pivotal in managing and addressing the challenges posed by insomnia. Furthermore, insomnia affects our behavior: we might become hyperactive or impulsive due to the loss of emotional control. Aggressiveness, loss of motivation, and a propensity for errors can also be outcomes of insomnia. However, one of the key aspects of insomnia is its impact on self-perception. Lack of sleep can lead to feelings of dissatisfaction or anxiety regarding one’s own sleep, adding to the cycle of negative consequences of this condition. Diagnosing Insomnia According to the International Classification of Sleep Disorders (ICSD-3) for diagnosing persistent insomnia aligned with DSM-5 criteria, symptoms must be present at least 3 days per week for a minimum of 3 months. Short-term insomnia (ICSD-3) or episodic insomnia (DSM-5) shares the same criteria as chronic insomnia but lasts less than 3 months. Hence, it’s crucial to keep a diary, marking nights when sleep difficulties arise. This not only helps gauge the frequency of issues but also provides a more accurate depiction for diagnosis and seeking effective solutions. Lastly, if sleep problems can be entirely explained by other conditions or disorders, they may not meet diagnostic criteria for insomnia. However, it’s essential to remember that insomnia can coexist with other mental disorders, and it’s not always the sole symptom as previously believed. Even if other disorders are the primary source, if insomnia is significant, medical practice should consider it as a separate, accompanying disorder necessitating its clinical intervention. Current Sleep History Analyzing the current sleep pattern plays a pivotal role in confirming the diagnosis and determining the best treatment for insomnia. This involves examining the sleep-wake schedule, sleep routines, nocturnal habits, and daytime activity. Let’s delve deeper into these aspects. Providing the doctor with a detailed report on sleep onset, frequency of awakenings, wake-up times in the morning, and time spent out of bed is crucial. Smartwatches and trackers excel in this task, provided they are worn consistently for at least 2 weeks during sleep for data collection. However, it’s worth noting that the accuracy of these devices is not confirmed, and your healthcare provider will likely offer more precise assessment tools for sleep duration and depth. Nevertheless, for observing trends (whether you slept more compared to previous periods), these devices can be quite suitable. Furthermore, it’s essential to inform the doctor about what happens when you can’t fall asleep or when you wake up. For instance, certain post-awakening habits, like snacking or watching TV, might negatively impact sleep quality. Engaging in such activities during wakefulness might not promote improved sleep and could create irregular wakefulness rhythms. Discussing these behaviors with the doctor is important as it provides crucial information for proper evaluation. While the sleep-wake schedule is important, it’s not sufficient for a definitive diagnosis. The doctor also requires your subjective perception of sleep quality, hence the importance of maintaining a sleep diary for more accurate information. Let’s explore the necessary information for a proper assessment of sleep quality. Sleep Diary We’ve discussed how collecting data on the frequency of insomnia episodes plays a crucial role in diagnosing and treating this disorder. Hence, the gold standard is maintaining a sleep diary for two weeks. A sleep diary should provide the doctor with key information, such as bedtime, lights out, sleep onset and awakenings, morning wakefulness duration, wake-up time, and overall perceived sleep quality. Occasionally, data on sedative and alcohol consumption are also important. This information aids in diagnosing insomnia and forms the basis for determining the individual nature of the problem. A good sleep diary should encompass the following parameters: While filling out a diary might seem laborious to some, some of these parameters can be effectively captured

Biologische leeftijd berekenen

Biological Age Blood Test

Biological Age Blood Test Read More »

Did you know that you can determine your biological age through a simple blood test? While your chronological age is based on your date of birth, a biological age blood test measures various biomarkers to determine how well your body is aging. By taking this test, you can gain valuable insights into your overall health and identify areas where you may need to make lifestyle changes to improve your biological age. So, why should you care about your biological age? Well, research has shown that people with a higher biological age than their chronological age are at a greater risk for age-related diseases like heart disease, Alzheimer’s, and cancer. However, the good news is that you can take steps to reduce your biological age and lower your risk of these diseases. Package of lab tests to calculate biological age: IN THIS ARTICLE 1 For whom is this product intended? 2 Discover Your True Biological Age with a Blood Test: Why Should You Get Tested? 3 Why should you trust Healsens to calculate your biological age? RELATED ARTICLES For whom is this product intended? Biological age is a measure of an individual’s health and physical condition that goes beyond their chronological age. While we all age, the rate and manner of aging can differ significantly between individuals, based on lifestyle habits, genetics, and other factors. Measuring biological age can help individuals understand how their bodies are aging and identify areas for improvement in their health habits. One tool for measuring biological age is Levine’s Phenotypic Age calculator, which uses a combination of biological markers to estimate an individual’s age at the cellular level. So, for whom is this product? In short, anyone who is interested in their health and wants to take a proactive approach to aging. Individuals who want to optimize their health and longevity may benefit from using Levine’s Phenotypic Age calculator. This tool can be particularly useful for individuals who are at higher risk for age-related diseases, such as heart disease or cancer, or who have a family history of such conditions. Furthermore, individuals who have experienced significant changes in their lifestyle or health status may also benefit from measuring their biological age. For example, if someone has recently quit smoking, started exercising regularly, or made significant changes to their diet, measuring their biological age can provide an objective measure of the impact of these changes on their health. Discover Your True Biological Age with a Blood Test: Why Should You Get Tested? But why should you purchase lab tests to calculate your biological age? The main reason is that it provides valuable information about your overall health status and can help identify areas for improvement. By knowing your biological age, you can make informed decisions about your health and lifestyle, such as increasing physical activity, improving diet, or reducing stress levels. Moreover, measuring biological age can help you detect potential health issues early on when they are more manageable. For example, if someone’s biological age is significantly higher than their chronological age, it may indicate that they are at higher risk for age-related diseases, such as heart disease or cognitive decline. Armed with this knowledge, you can take proactive steps to reduce the risk and improve your overall health and well-being. In conclusion, measuring biological age using Levine’s Phenotypic Age calculator can provide individuals with valuable insights into their health and aging process. By understanding your biological age, you can take a proactive approach to your health and make informed decisions about your lifestyle habits. With this information, you can optimize their health and well-being and potentially increase their lifespan. » Explore everything about the significance of High Platelet Count results mean. How to Order Biological Age Blood Test? If you are interested in checking your biological age, you can easily purchase a blood test kit from Healsens. 1 Download the Healsens App from Google Play or the App Store, depending on your device. 2 Complete the registration process in the app. 3 Go to the “Risks” page via the bottom menu of the application. 4 Tap on the test you need — ”Levine’s Phenotypic Biological Age” 5 Tap on the “Add to Cart” button inside the test page and proceed with the ordering process. Process of taking blood tests in: Labplusarts ↗ Bloedwaardentest ↗ » Unlock Optimal Health: Discover How a Personalized Healsens General Check-up Plan Can Transform Your Well-being. Note If you want to assess your biological age but are not residing in the Netherlands or have opted for a different laboratory, Healsens cannot upload your blood test results for you. Nevertheless, you have the option to undergo the required tests at any laboratory in your country and manually input the obtained results into the application. Healsens will open more opportunities for you to naturally normalize your blood test results. Furthermore, you gain full access to investigate your health risk assessment based on the provided data. Why should you trust Healsens to calculate your biological age? Healsens is committed to providing you with accurate and reliable results that you can trust. We partner with Medical Laboratories Dr. Stein & Collegae, a highly respected and accredited laboratory in the Netherlands, to ensure that your blood samples are processed with the utmost care and accuracy. Lab Stein has an excellent reputation within the Dutch healthcare sector. With more than 20 medical specialists (laboratory doctors), chemists, biologists, doctors-microbiology etc. and 600 employees, the laboratory is one of the three largest medical laboratories in Europe. They carry out more than 5 million tests per year. Furthermore, we use Levine’s Phenotypic Age calculator to estimate your biological age. This algorithm has been proven with high accuracy in multiple studies and is widely accepted as a reliable method for calculating biological age. At Healsens, we understand that not everyone is comfortable with preventive medical examinations without a referral from their general practitioner. That’s why we work with our partners to ensure that our tests are conducted with the highest standards

Анализы крови в Нидерландах

Ordering Blood Tests Netherlands: A Comprehensive Guide

Ordering Blood Tests Netherlands: A Comprehensive Guide Read More »

Are you looking to get blood tests done in the Netherlands or undergo regular general health checkups? With the Healsens mobile app, residents of the Netherlands can now order blood tests without a referral from a general practitioner. This functionality enables you to obtain the essential tests you need, eliminating the need for a doctor’s visit. Simplify your healthcare journey with our blood test service in the Netherlands. RELATED ARTICLES 4 Receive Your Kit: A personalized test kit will be delivered to your provided home address. The test tubes will come equipped with a barcode linked to your research, and they will be specially prepared with liquid for shipment. It’s crucial to verify all your data to ensure accuracy. 5 Select a Test Center: Upon receiving a confirmation email, you’ll be prompted to choose a nearby blood test center where you can have your blood sample taken. It’s necessary to schedule an appointment and bring along your referral letter, test kit, and ID to the center. Trained professionals will collect the blood samples, ensuring that all tubes in your test kit are filled. 6 Send Your Kit: After your blood sample is collected, you’ll need to return the test kit to the lab using the prepaid packaging provided. Simply send the collection materials with the lab form as a letter, without registration or a track & trace code. Medical mail services in the Netherlands are highly efficient, ensuring the safe delivery of your samples to the laboratory. 7 Get Your Results: You will receive the results of your lab tests directly in the app (be sure to enable notifications to avoid missing results). Alternatively, you will receive your results via email. Most lab test results are typically available within a few days, up to a maximum of 10 working days. Your lab test results can be utilized to enhance your health through tailored advice on nutrition, supplements, and lifestyle changes. Healsens collaborates with various health coaches, specialists, and therapists who offer complementary care. The Healsens app grants access to personalized health plans, coaching, and support to assist you in achieving your health objectives. » Discover how to monitor and enhance your health with Healsens preventive checkup plan. How Healsens Saves Your Money* The application’s algorithm intelligently selects the most cost-effective lab test packs based on your chosen examinations, ensuring efficient use of your resources. If you prefer a customized examination plan, the algorithm also aids in identifying the most financially viable options for you. In the risk calculators section, you’ll also find the option to request a package of analyses for risk assessment. Here, you can conveniently order a package of analyses for DNAm PhenoAge or AIP calculator, among others. Why should you trust Healsens? Healsens is committed to providing you with accurate and reliable results that you can trust. We collaborate with Medical Laboratories Dr. Stein & College, a highly respected and accredited laboratory in the Netherlands, to ensure that your blood samples are processed with the utmost care and precision. Lab Stein has an excellent reputation within Dutch healthcare. With over 20 medical specialists (laboratory physicians), chemists, biologists, doctors in microbiology, and 600 employees, the laboratory is one of the three largest medical laboratories in Europe. They conduct more than 5 million tests annually. Availability: Our laboratory test package is cost-effective and utilizes affordable laboratory tests, making it accessible and user-friendly. At Healsens, we understand that not everyone feels comfortable with preventive medical examinations without a referral from their general practitioner. That’s why we work with our partners to ensure that our tests are conducted to the highest standards of care and confidentiality.

general check-up

Get a Personalized General Check-up: Your Key to Peace of Mind and Health

Get a Personalized General Check-up: Your Key to Peace of Mind and Health Read More »

Preventive medicine is rapidly advancing towards a more personalized approach. This shift, driven by international medical organizations, prioritizes disease prevention and tailors clinical recommendations to individual risk factors. However, many medical centers still offer a standard list of blood tests to all patients, overlooking these unique risk factors and updated guidelines. This generalized approach can delay the diagnosis of various diseases. It’s essential to know which specific blood tests should be part of your General Check-up to avoid missing potential illnesses. Moreover, understanding the appropriate tests can help you avoid unnecessary procedures, false diagnoses, and treatments, ultimately contributing to a sense of peace and well-being. Selecting a General Check-up that aligns with your personal health needs ensures you receive the most accurate and beneficial care. This article was last reviewed by Svetlana Baloban, Healsens, on January 24, 2022. This article was last modified on 3 March 2023. Screening vs. Diagnostic Tests When visiting a doctor, the tests you undergo can be classified into two categories: diagnostic and screening tests. Diagnostic tests are prescribed based on specific complaints to identify the underlying cause of symptoms. Screening tests, on the other hand, are recommended even in the absence of symptoms, aiming to detect diseases early based on age, sex, family history, or other risk factors. Personalized Screening with Healsens IN THIS ARTICLE 1 Screening vs. Diagnostic Tests 2 Personalized Screening with Healsens 3 Factors in General Check-up Decisions 4 Healsens General Check-up Plan RELATED ARTICLES Healsens adopts guidelines from reputable medical organizations like the US Preventive Services Task Force and the American Society of Clinical Oncology to personalize your General Check-up. By asking about your habits, weight, height, waist circumference, and more, Healsens considers individual risk factors to create a tailored preventive checkup plan. This ensures that your General Check-up is not only thorough but also relevant to your specific health needs. Factors in General Check-up Decisions Several factors determine the necessity and appropriateness of screening tests in a general check-up: Medical guidelines are continuously updated to reflect the latest research. Healsens leverages these guidelines to provide a list of necessary tests based on your individual risk factors, including: Interesting Fact Do you know that there are several methods for testing mutations in the BRCA1 and BRCA2 genes? The most accessible and inexpensive one is PCR testing for mutations in the BRCA1 and BRCA2 genes. And as you might guess, it is the least accurate. Only 5% of all cases of mutations will be diagnosed by this testing method. Therefore, if you have a family history of breast or ovarian cancer, the NGS method is used as a screening method. Healsens General Check-up Plan The Healsens General Check-up plan offers a comprehensive and personalized approach to preventive health maintenance. By incorporating the latest medical guidelines and research, Healsens ensures you receive the most appropriate screening tests for your unique health needs. This proactive approach not only enhances early detection and prevention of potentially life-threatening illnesses but also brings a sense of peace and well-being. Healsens’ personalized General Check-up plan considers your individual risk factors, leveraging up-to-date guidelines to offer a tailored, comprehensive health screening. This approach helps you stay ahead of potential health issues while avoiding unnecessary interventions, ensuring your peace of mind and optimal health.

hdl-cholesterol waarde

How To Increase Good Cholesterol

How To Increase Good Cholesterol Read More »

Dietary strategies to lower levels of bad LDL cholesterol can negatively affect HDL cholesterol, which is quite common, unfortunately. However, it’s important to know how to increase good cholesterol to maintain a healthy heart. Therefore, there are a number of clinical strategies for treating atherosclerosis and boosting HDL cholesterol levels. Let’s take a look at some of these strategies and also explore what foods can help with increasing good cholesterol. This article was last reviewed by Svetlana Baloban, Healsens, on January 24, 2020. This article was last modified on 5 April 2022. How does HDL cholesterol affect cardiovascular disease? We have written more than once about the importance of a healthy lipid profile, if, in the future, you do not want to experience atherosclerosis, coronary heart disease, and stroke. But why did we decide to write specifically about good HDL cholesterol? Let’s start with numbers. In prospective epidemiological studies, each 1 mg/dL increase in HDL is associated with a 2–3% reduction in risk of coronary heart disease. This ratio is not affected by the level of bad LDL cholesterol and triglycerides due to the ability of good HDL cholesterol to reverse cholesterol transport. Let’s see what it means. So, reverse cholesterol transport (RCT) is a pathway through which cholesterol is transported from the artery walls to the liver so it can be excreted from the body. It is through this process that the body reduces the amount of plaque buildup in vessel walls and reverses atherosclerosis. Not surprisingly, data from the Framingham Heart Study showed that people with the highest HDL levels have the lowest risk of developing heart disease. IN THIS ARTICLE 1 How does HDL cholesterol affect cardiovascular disease? 2 How to increase good HDL cholesterol? 3 Diet Plan to Increase HDL 4 Aerobic exercise RELATED ARTICLES HDL Normal Range In Adult Treatment Panel III (ATP III) guidelines, the HDL cut-off for healthy individuals has been increased to at least 40 mg/dl in men and to 50 mg/dl in women. In general, the following HDL normal range was announced: <40 mg/dL ≥60 mg/dL Low HDL cholesterol High HDL cholesterol There are several factors that lead to low HDL cholesterol, namely: In our previous articles, we talked about ways to reduce bad cholesterol. Now it’s time to talk about how to increase good HDL cholesterol. Let’s start with the analysis of drug treatment. How to increase good HDL cholesterol? Medication to increase HDL Nicotinic Acid or Niacin The most widely used drug to increase HDL levels is nicotinic acid or niacin. Niacin is thought to reduce the risk of cardiovascular disease by lowering LDL cholesterol and increasing good HDL cholesterol. Therefore, niacin is often recommended for patients with low HDL cholesterol levels. One study reports that niacin can increase HDL levels by 25-35% at the highest doses. And if we talk about the situation of atherogenic dyslipidemia, then studies show a strong trend towards a decrease in the risk of coronary artery disease. It should be remembered that atherogenic dyslipidemia is characterized by low levels of high-density lipoprotein (HDL), high levels of triglycerides, and a high number of low-density lipoprotein (LDL) particles. Despite the apparent ability of niacin to increase HDL levels and lower LDL, not everything is so rosy. Studies have also shown that niacin can cause serious adverse events. Thus, among participants who received niacin/laropiprant tablets, there was a 55% increase in diabetes control disorders that were considered serious. » Discover how to lower your “bad” cholesterol. Ezetimibe Another drug that affects reverse cholesterol transport is ezetimibe. In a recent study, ezetimibe was shown to enhance macrophage reverse cholesterol transport in hamsters. However, as with niacin, ezetimibe as a primary agent has not been shown to improve patient outcomes. The ezetimibe and simvastatin ENHANCE study was designed to show that ezetimibe can reduce the growth of fatty plaques in the arteries. Patients with genetically high cholesterol were given only statins or ezetimibe plus simvastatin. The doctors then measured their LDL cholesterol levels and examined their arteries to measure plaque growth. As a result, LDL cholesterol decreased more with combination therapy, it did not improve the condition of the arteries. In fact, after 2 years of therapy, intima-media thickness increased more in the ezetimibe/simvastatin group. However, it is worth noting that patients with high cholesterol due to genetics may not represent the entire population. One way or another, but further studies of these drugs are currently being conducted. The results will help doctors conclude whether these drugs are an effective strategy for treating atherosclerosis. In any case, for people with high risk for CVD, who have excess weight, diabetes, metabolic syndrome, or a family history of CVD, it is worth discussing medical options with a cardiologist. Diet Plan to Increase HDL One of the most intriguing areas of research within treating atherosclerosis and heart disease is dietary intervention, including how to increase good cholesterol. Most doctors agree that diet is one of the most effective ways to prevent atherosclerosis, and that making dietary changes can help improve HDL cholesterol levels. This is true in reverse as well. Thus, additional research confirms that a Western diet high in meat, butter and dairy products plays a large role in the high rate of death from cardiovascular diseases. The most common dietary intervention is the consumption of fish. This is primarily because fish is correlated with an improved omega-3/omega-6 ratio and cardiovascular health. For example, a summary of dietary data showed that saturated fatty acid intake increased good HDL cholesterol without increasing bad LDL cholesterol. Other researchers have taken this idea further and even attempted to reverse cardiovascular disease through dietary interventions. The effect of plant-based nutrition on HDL cholesterol Vegetables and a vegan diet play a big role in normalizing your lipid profile and prevent atherosclerosis. The American Heart Association have released specific diet guidelines to prevent cardiovascular disease: In addition, studies show that a plant-based diet can help with regression of stenoses. So, in the study, 22 patients with severe coronary heart disease were observed

mammogram screening guidelines

MAMMOGRAM SCREENING GUIDELINES

MAMMOGRAM SCREENING GUIDELINES Read More »

In one of our previous articles, we wrote that mammography (MMG) is a screening diagnostic method for breast cancer. Today, we would like to expand on this topic and have invited a specialized specialist to share information about MMG and the current mammogram screening guidelines being used. This article was written by Y. Timovskaya, Ph.D., doctor oncologist of the highest category, Member of ESMO with the help of A Galishyna, head of the diagnostic department of the Specialized Breast Center, a doctor of radiation diagnostics, member of ESR, EUSOBI. This article was last modified on 10 August 2021. It has been proven that regular examinations increase the rate of early detection of breast cancer. 👉 But are all examination methods (examination, mammography, ultrasound) equally effective for the early detection of breast cancer?👉 And how often should they be applied: annually, every six months, or are there other options? Today we will deal with these issues. Early Diagnosis of Breast Cancer For early detection of breast cancer, especially preclinical forms, the effectiveness of mammography (MMG) and magnetic resonance imaging (MRI) of the mammary glands with contrast enhancement has been proven. Ultrasound examination of the mammary glands is a useful addition to them. When choosing a diagnostic method, there is no universal approach that would suit everyone. The results of breast cancer treatment directly depend on the stage at which the treatment of this disease is started. The smaller the stage, the shorter, cheaper, and more effective the treatment. Therefore, the whole world is fighting to identify the early, if possible, preclinical stages of breast cancer (we wrote about what clinical breast cancer is in a separate article). IN THIS ARTICLE 1 Early Diagnosis of Breast Cancer 2 Ultrasound breast screening and Mammogram: definition 3 How to Choose Diagnostic Methods 4 Mammogram vs Ultrasound 5 Mammogram screening guidelines 6 What you need to tell the doctor to determine the research method At the same time, it is necessary to take into account the patient’s age, complaints, anamnesis, clinical examination data, and the results of previous medical tests. Ultrasound Breast Screening and Mammogram: definition ✔ Mammography (MMG) is an X-ray method for breast examination, which is the gold standard for diagnosing breast cancer. It perfectly detects microcalcifications, one of the early signs of breast cancer. The most important thing when using MMG is the fact that even standard views allow you to visually assess the full volume of an organ. ✔ Ultrasound – ultrasound examination of breast tissue, an additional diagnostic method. Suitable for patients with increased density of breast tissue (women under 35-40 years old). Therefore, it may be more appropriate for patients under 35-40 years of age to have an ultrasound scan rather than mammography (MMG). It is also the best method for fragmentary assessment of breast tissue. It is also used for the differential diagnosis of some formations. These, for example, include formations with a clear outline, identified on mammography. Each of these methods has advantages and disadvantages. There are no absolute contraindications to their implementation. How to Choose Diagnostic Methods As we wrote above, each clinical case requires an individual approach in the selection and examination sequence. So, for example, if a patient has complaints, her examination is diagnostic in nature. In this case, the doctor’s task is to choose the most appropriate diagnostic method. The aim will be to find out the reason for the complaints, the nature of the process, and the extent to which it has spread. It’s worth saying that a multimodal approach is often used. In such cases, a combination of several methods is used (MMG + ultrasound, MMG + MRI, using interventional techniques). It is also important to note that doctors sometimes need to apply special techniques within the same research method. For example, in the case of MMG, these are spot view, magnification view(s), Cleopatra’s view, etc. But in any case, the doctor is responsible to choose the appropriate diagnostic methods and techniques. Therefore, it is very important to contact specialists who can use the entire arsenal of diagnostic methods. Is it possible to avoid examinations if there are no complaints from the breast? The American Society of Breast Surgeons says that all women over the age of 25 must have a formal breast cancer risk assessment. You can do it yourself, or go through the risk assessment according to the NCCN guidelines in Healsens (below there will be links to download the app). After such an assessment is made, categories of patients without complaints should undergo screening. If a woman is not at risk, then such examinations can be started from the age of 40+. But we’ll talk more about mammogram screening guidelines below. If the risk of breast cancer is above average, then annual screening mammograms should be started at an earlier age, and in addition to mammography, additional examinations may be required. Mammogram vs Ultrasound It is worth pointing out what the limitations are for each diagnostic method. Thus, it will become more obvious what is decisive when choosing a diagnostic method. So, for ultrasound, the following limits are distinguished: Since ultrasound assesses the gland tissue fragmentarily, section by section, for patients with large breast sizes, this method is also not very suitable. This is due to the fact that there is a high risk of missing small formations. Mammography is not recommended without direct indications (suspected cancer) during pregnancy and lactation. In addition, in young patients, the diagnostic value of MMG decreases. This is due to the fact that young women have a higher density of breast tissue. And finally, we add that MMG is also ineffective in the presence of inflammatory diseases of the mammary glands. Mammogram screening guidelines At the moment, medical guidelines aim for an individualized approach, taking into account personal risks. Generally, the higher the risk of breast cancer, the earlier and more often screenings are recommended. So, for example, the American Cancer Society divides women into risk groups. For Women at Increased Risk of Breast

what is metabolic syndrome

What Is Metabolic Syndrome?

What Is Metabolic Syndrome? Read More »

Metabolic syndrome is an unhealthy metabolism that leads to fatal diseases such as heart attacks, diabetes, and cancer. Moreover, this condition affects more than a fifth of the US population and about a quarter of the European population. Even though its prevalence in South-east Asia is lower, it is still rapidly moving towards the rates of the western world even there. It should be understood that metabolic syndrome is a problem for not only overweight people. So, in 40 out of 70 percent of people with normal weight, doctors diagnose metabolic disorders. This is at least related to an increase in waist circumference or visceral obesity. So what is metabolic syndrome? How do you know if you are at risk? How can lifestyle help prevent this condition and what is the treatment aimed at? This article was last reviewed by Svetlana Baloban, Healsens, on January 24, 2020. This article was last modified on 4 September 2021. What is Metabolic Syndrome? Essentially, metabolic syndrome is the simultaneous presence of several conditions, such as obesity, hyperlipidemia (abnormal levels of cholesterol and / or lipoproteins), diabetes and / or hypertension. This combination was first described back in the late 1960s. Nowadays, medical organizations say that even a few of the risk factors are sufficient. Let’s take a look at which conditions are referred to as metabolic syndrome and which of the factors are more influential. Metabolic Syndrome Criteria The NCEP ATP III panel identified 3 of 5 risks of the next metabolic syndrome criteria: At the same time, the International Diabetes Federation names narrower ranges: IN THIS ARTICLE 1 What is Metabolic Syndrome? 2 What causes metabolic syndrome? 3 Metabolic Syndrome treatment 4 Supplements or Nutraceuticals for Metabolic Syndrome RELATED ARTICLES These are recommendations for the European race. For Chinese, Japanese and South Asians, a waist circumference of ≥90 cm for men is at risk. Note that weight is not taken into account, just the waist circumference. This is no accident. In the next chapter, we will review in detail why so much attention is paid to waist circumference. Other risk factors include the following indicators: 2) elevated triglycerides (≥150 mg/dl);  3) low HDL cholesterol (<40 mg/dl in men, <50 mg/dl in women);  4) hypertension (≥130/≥85 mmHg); and  5) impaired fasting glucose (≥110 mg/dl). The American Heart Association reports a level of risk fasting glucose levels at ≥100 mg / dL. At the same time, the pathophysiology of this syndrome remains a subject of continuing controversy. However, despite the lack of knowledge, researchers have identified visceral obesity and insulin resistance as the most important causative factors. Central obesity or visceral obesity is readily assessed at waist circumference and is independently associated with each of the other components of metabolic syndrome. The second significant factor in the development of this disease is an increase in glucose levels (hyperglycemia). However, even a small increase, both on an empty stomach and after a meal, increases the risk of cardiovascular disease and mortality. In addition, a prospective Quebec study has found that even with no increase in blood sugar, elevated insulin levels (i.e., insulin resistance) are associated with a risk of coronary heart disease. In addition, insulin resistance also contributes to the development of hypertension due to the loss of the vasodilator effect of insulin and vasoconstriction. What causes metabolic syndrome? The pathogenic mechanisms of MetS are complex and yet to be fully elucidated. However, the wide variation in geographic distribution of MetS emphasizes that the consumption of excess calories and lack of physical activity are the major contributors to the development of the disease. Moreover, visceral obesity is the key trigger for most pathways involved in metabolic syndrome. It is worth saying here that visceral fat may not be visible to the naked eye, but it is the fat that envelops the heart, liver and other organs, representing a real threat. By itself, visceral fat behaves very differently from subcutaneous fat. For example, visceral fat deposits contribute to insulin resistance. This is due to the fact that the visceral process of lipolysis leads to an increased supply of free fatty acids (FFAs) to the liver. This, in turn, increases synthesis of triglycerides and production of apolipoprotein B, the carrier of “bad cholesterol”. Ultimately, the “bad” particles become smaller, denser and much more numerous and easily penetrate the vascular endothelium, where they cause irreparable damage. Very high levels of “bad” LDL cholesterol and low levels of “good” cholesterol are indirect effects of insulin resistance. If you add to this an increase in triglycerides (atherogenic dyslipidemia), then even at a normal weight, you will get central obesity with the same high risk of death as obesity. Thus, as you can see, visceral fat, elevated insulin levels, and an unhealthy lipid profile (unhealthy cholesterol levels) are linked to each other. And all this leads to problems with cardiovascular diseases, diabetes, hypertension. It is not a surprise why in Healsens, in addition to monitoring weight, we recommend monitoring waist circumference. Metabolic Syndrome treatment Exercise As previously described, MetS results from increased caloric intake out of proportion to metabolic requirements. That is why lifestyle changes are imperative to manage the main risk factors. The first step in reducing risk factors is maintaining ideal body weight. Accordingly, if BMI is increased, then weight loss is an important preventive and therapeutic strategy. However, weight loss doesn’t have to be a goal by itself. As we wrote above, people whose weight within the normal range may have visceral obesity, which can be measured by checking the circumference of the waist. In this case disease prevention will imply reducing visceral fat without losing weight. The good news is that numerous studies show that it suffice to add physical activity to help the problem. In fact, physical exercise can reduce visceral adipose tissue by 6.1%. Moreover, exercise itself is effective in maintaining muscle mass and facilitating mobility. As for exercise, if there is nAs for exercise, if there is no personal trainer to consult, 30-60 minutes of moderate-intensity exercise per week will

Biologische leeftijd berekenen

Biological Age By Dnam Phenoage

Biological Age By Dnam Phenoage Read More »

Aging is an inevitable process, but there are differences in susceptibility to age-related diseases and the risk of death among people of the same chronological age. This means that different people have differences in the rates of biological aging. To better understand the differences between biological and chronological age, it is necessary to measure biological aging. For this purpose, various calculators of biological age have been developed, which allow us to assess the impact of lifestyle on the aging process. One such biomarker is DNAm PhenoAge, a biological age biomarker developed at Yale University. DNAm PhenoAge significantly outperforms previous measurements in predicting various aging outcomes, including all-cause mortality, cancer, health span, physical functioning, and Alzheimer’s disease. This article was last reviewed by Svetlana Baloban, Healsens, on March 4, 2023. This article was last modified on 28 February 2023. What is Biological Age by DNAm PhenoAge? DNAm PhenoAge is an aging biomarker developed at Yale University that measures a person’s biological age. It is based on data from NHANES III and includes 9 biomarkers, such as the number of red and white blood cells, as well as a person’s chronological age. It is capable of predicting risks of various aging outcomes in tissues and cells and provides insight into important pathways of aging. The DNAm PhenoAge biomarker has been validated in NHANES IV as a strong predictor of morbidity and mortality risk, and has been tested for accuracy in calculations on several patient cohorts taking into account age-related outcomes. So, the biological age according to DNAm PhenoAge is a fairly accurate predictor of healthspan and lifespan at the epigenetic level. This means that biological age according to DNAm PhenoAge can be used as an indicator of a person’s health status before any pathologies appear. For most people, this can be a good indicator of the real state of their health before they encounter any diagnoses. IN THIS ARTICLE 1 What is Biological Age by DNAm PhenoAge? 2 How to use biological age calculator? 3 Is it possible to reverse biological aging? RELATED ARTICLES How to determine your biological age? To calculate biological age using DNAm PhenoAge, several simple blood tests need to be taken, including: Biological Age Blood Test Units Albumin ↑ Liver g/L Creatinine ↓ Kidney umol/L Glucose, serum ↓ Metabolic mmol/L C-reactive protein ↓ Inflammation mg/dL Lymphocyte percent ↑ Immune % Mean cell volume (MCV) ↓ Immune fL Red cell distribution width (RDW) ↓ Immune % Alkaline phosphatase ↓ Liver U/L White blood cell count (WBC) ↓ Immune 1000 cells/uL Age Years Table 1. Phenotypic aging measures In general, the DNAm PhenoAge biomarker can be determined through inexpensive blood tests, making it accessible to most people. After receiving the test results, online calculators can be used to calculate one’s biological age based on DNAm PhenoAge. This is convenient not only for a one-time calculation but also for monitoring the dynamics of biological age over time. Below you can see the biomarkers of our user who, over the course of several years, was able to reduce their biological age by 21 years compared to his chronological age with the help of changes in their diet and physical activity. Albumin Creatinine Glucose hs C-react Protein Lymphs (Lympocyte, % not absolute) MCV (Mean Cell Volume) RDW (Red Cell Dist Width) or Red Blood Cell Distribution Width (RDW-SD)? Alkaline Phosphatase WBC (White Blood Cells) Age ↑ ↓ ↓ ↓ ↑ ↓ ↓ ↓ ↓ 49 60.000 4.6 0.3 43.2 90 11.8 40 4.2 49.1 g/L umol/L mmol/L Ln(mg/L) % fL % U/L 10^3 cells/uL years Table 2. Lab test results of a 49-year-old man whose biological age is 21 years less than his chronological age. How to use biological age calculator? The calculated biological age by Levine’s DNAm PhenoAge is compared to the current chronological age. If the result is lower than your passport age, it is not only good news but also an indicator that your lifestyle positively affects your health. But what if the situation is the opposite? The most important thing is not to get upset! Now you know that you should pay attention to your health, and it makes sense to review your lifestyle. Thanks to the fact that there are several biomarkers, you can see what exactly to focus on. In addition, by making changes to your lifestyle, you can evaluate each individual indicator in addition to your biological age. To understand whether the dynamics are positive for each indicator, let’s return to Table 1. Each biomarker contains arrows ↓ or ↑. These arrows indicate a positive trend. For example, the downward arrow “↓” next to the glucose level indicates that lower levels of glucose indicate a younger biological age. Is it possible to reverse biological aging? New research shows that we can actually reverse biological aging through diet and lifestyle. In 2021, it was published the results of a pilot randomized clinical trial that demonstrated the ability to reverse biological age and was confirmed by objective outcomes. This is a very interesting observation, and there are several factors that can influence biological aging. Our lifestyle, comprising factors such as diet, physical activity, and stress, is considered a crucial element that affects biological age. In an effort to reverse the biological age in humans, researchers utilized a combination of diet, physical activity, and stress resilience techniques. The study monitored a group of individuals who were enrolled in a health program featuring a balanced low-calorie diet, daily 30-minute exercise at 60-80 percent intensity of maximum perceived exertion, and breathing exercises twice a day. Additionally, the study also focused on the quality of sleep, and it was discovered that insomnia was linked to an increase in DNAmAge clocks. Another study also found a connection between poor sleep quality/less sleep hours and accelerated aging in a small sample of 12 college female students. In the end, those who adhered to the recommended health program showed a reduction in age by 9 years, indicating that by maintaining a balanced diet, regular physical activity, and effective stress management,

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