Cancer Prevention

Cancer prevention includes actions to lower the risk of getting cancer. This can include maintaining a healthy lifestyle, avoiding exposure to known cancer-causing substances, and taking medicines or vaccines that can prevent cancer from developing.

Treatment For Vitamin D Deficiency

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Understanding the importance of vitamin D for health at any age is crucial. Since low levels of vitamin D are common, it is important to know how to treat it. We will discuss various ways to improve health through sunlight exposure, proper nutrition, and the use of vitamin D supplements as part of the treatment for vitamin D deficiency. Additionally, we will explore how individual characteristics can influence the success of achieving healthy vitamin D levels, as well as determine safe dosages for its maintenance. This article was last reviewed by Svetlana Baloban, Healsens, on October 24, 2020. This article was last modified on 29 October 2020. Let us start with how we define vitamin D deficiency. In summary, a deficiency occurs when the serum 25-hydroxyvitamin D level is less than 20 ng/ml (50 nmol/L). If your serum 25-hydroxyvitamin D level is between 20 and 30 ng/ml (50 to 75 nmol/liter), then we are talking about vitamin D insufficiency. Values of less than 10 ng/ml refer to severe vitamin D deficiency. We will analyze the approach to treat this deficiency separately. Treatment for vitamin D deficiency Sunbathing Sunbathing, mentioned in the article about the influence of vitamin D on health, is an excellent way to compensate for vitamin D deficiency. Sunlight (ultraviolet) promotes the formation of about a dozen beneficial compounds, including not only vitamin D but also nitric oxide (NO5), which is beneficial for reducing blood pressure, cardiovascular diseases, and metabolic syndrome. The skin contains significant reserves of nitric oxide, which, when exposed to ultraviolet light, can be converted into NO and enter the systemic circulation. Studies on humans show that this process can cause dilation of arterial vessels and reduction in blood pressure. IN THIS ARTICLE 1 Treatment for vitamin D deficiency 2 Vitamin D Deficiency Treatment Using Supplements 3 Maintenance Dose of Vitamin D 4 Monitoring Vitamin D Levels RELATED ARTICLES It is also noted that the impact of ultraviolet radiation can suppress clinical symptoms of multiple sclerosis independently of vitamin D synthesis . Sunlight is also beneficial for maintaining healthy erectile function. However, it is worth remembering that UV radiation remains a proven carcinogen. What to do in this situation? It is recommended to consider the option of “healthy sun exposure”, when you are in the sun during the safest times – before 10 in the morning and after 4 in the evening. It is important to remember that sunscreen with a sun protection factor of 30 can reduce vitamin D synthesis in the skin. Additionally, people with naturally dark skin have built-in sun protection and require at least three to five times longer exposure to produce the same amount of vitamin D. Choose the safest times for sunbathing without sunscreen. Food Another way to increase the level of vitamin D in the body is through the consumption of food products. Very few foods naturally contain or are enriched with vitamin D. However, in combination with sunbathing, food products can also be beneficial. Pay attention to foods such as fatty fish (salmon, mackerel, tuna), egg yolks, cheese, liver, and vitamin D-fortified dairy products and cereals – they can become a good source of this vitamin. In addition to sunbathing, in case of vitamin D deficiency (especially at critical levels when the level of 25(OH)D is less than 20 ng/ml), it is advisable to take vitamin D in the form of supplements. It is worth noting that the increase in the level of 25(OH)D when taking vitamin D supplements is highly individual. In the next chapter, we will delve into the issue of vitamin D dosages through supplements recommended at present. Vitamin D Deficiency Treatment Using Supplements Vitamin D deficiency is defined when the level of 25(OH)D is below 20 ng/mL. It is important to realize that unprotected sun exposure is the primary source of vitamin D for both children and adults. Vitamin D synthesized in the skin can remain in the blood at least twice as long as vitamin D obtained from external sources. However, if opportunities for sunbathing are unavailable, considering vitamin D supplementation becomes advisable. The amount of vitamin D needed to treat deficiency largely depends on the degree of deficiency and key risk factors. Let’s delve into clinical recommendations for treating vitamin D deficiency using supplements. Research findings indicate a rate of increase in the level of 25(OH)D in serum of approximately 0.4 ng/mL/μg/day. This means that intake of 100 IU/day of vitamin D increases the level of 25(OH)D in serum by less than 1 ng/mL. For instance, if your level of 25(OH)D in serum is 15 ng/mL, an additional daily intake of about 1500 IU of vitamin D2 or vitamin D3 is required to achieve and maintain a level of 30 ng/mL. However, to achieve a similar increase in the level of 25(OH)D in serum among individuals with obesity, two to three times more vitamin D is required. Vitamin D can be taken on an empty stomach or with meals, and dietary fats are not required. Taken three times a year, weekly, or daily, vitamin D can be effective in maintaining the level of 25(OH)D in serum for both children and adults. » Discover everything about what your cholesterol results mean. How much vitamin D should I take if I’m deficient? So, the amount of vitamin D needed to treat a deficiency depends largely on the degree of the deficiency and the underlying risk factors. Initial supplementation with Vitamin D3 for 8 weeks, either 6,000 IU daily or 50,000 IU weekly, can be considered. When the vitamin level exceeds 30 ng/ml, the daily maintenance dose will be 1500 to 2000 IU. If after 8 weeks your level of 25(OH)D in the blood has not increased, it is recommended to undergo testing for celiac disease or hidden cystic fibrosis. Higher-risk adults may require higher starting doses of vitamin D3. These people include African Americans, Hispanics, people with obesity, chronic illness, and taking certain medications. Typically, your doctor may prescribe 10,000 IU of vitamin per day. For such people,

breast cancer risk factors

THE MAIN RISK FACTORS OF BREAST CANCER

THE MAIN RISK FACTORS OF BREAST CANCER Read More »

1 in 8 women will develop breast cancer (BC) in their lifetime. More than 2 million new cases of this disease are diagnosed worldwide every year. There are of course breast cancer risk factors. What do you need to know to prevent illness? Is it possible to reduce your own risk of developing breast cancer? Let’s find out. Written by Y. Timovskaya, Ph.D., doctor oncologist of the highest category, Member of ESMO. Together with @ Galishina Anna – Head of the Diagnostic Department of the Specialized Breast Center, doctor of radiation diagnostics of the highest category, member of ESR, EUSOBI. 8 major risk factors It’s possible to conditionally identify the main factors in the development of breast cancer. There are only 8 of them! Of course, in general, there are many more risks and we have already written about some little-known ones. But the most significant are the following: IN THIS ARTICLE 1 8 major risk factors 2 New risks 3 Why understand your risk factors? 4 Variable and permanent breast cancer risk factors 5 Patient stories RELATED ARTICLES 6. Hyperestrogenemia (increased concentration of estrogens in the blood), especially associated with the intake of hormonal drugs. And these are combined oral contraceptives (COCs), and hormone replacement therapy (HRT), and IVF. 7. Failure to comply with the healthy lifestyle rules, which leads to metabolic disorders. 8. Not having children or lactation or late childbirth. New risks In addition to the main risks, there are few that we are able to influence. They include: 👉 Low level of vitamin D. Research suggests that women with low levels of vitamin D have a higher risk of breast cancer. This happens because vitamin D may play a role in controlling normal breast cell growth and may be able to stop breast cancer cells from growing. 👉Exposure to Chemicals in Cosmetics So, research strongly suggests that at certain exposure levels, some of the chemicals in cosmetics may contribute to the development of cancer in people. Such substances include parabens (the most common are methylparaben, propylparaben, ethylparaben and butylparaben) and phthalates. 👉Exposure to Chemicals in Food There’s a real concern that pesticides, antibiotics, and hormones used on crops and livestock may cause health problems in people, including an increase in breast cancer risk. Now let’s talk about why we need all this information and what is the practical use of it? Why understand your risk factors? Do all factors in the breast cancer development lead to the development of breast cancer? No. Did all breast cancer patients have all these risk factors? No either. At the same time, a combination of risk factors increases the risk of developing breast cancer. However, it is not yet possible to determine exactly which of 8 women will develop the disease. Yet doctors talk about the importance of understanding risk factors. But why? There are situations when a woman has all the risk factors, and at the same time, she will never get sick with this disease. On the other hand, there are diametrically opposite situations when a woman does not have any risk factors except the first one, and she still gets breast cancer. However, such situations are marginal. They are located at the edges of the variation row for breast cancer patients. In most cases, that is in 80% of patients with breast cancer, known risk factors played a role in the disease development. Thus, women very often unconsciously provoked progressing tumor processes through their actions. And a major part of the cause of this problem was ignorance. In other words, many people have never heard of risk factors that subsequently cost them their health. Therefore, all over the world, the information war against breast cancer is recognized as one of the most effective mechanisms to reduce mortality from this disease. Variable and permanent breast cancer risk factors It should be noted that risk factors can be divided into two groups. The first one includes those that we cannot affect, such as gender, age, family history, and the presence of gene mutations. In this case, if you are aware of them, your doctor should adopt an individual preventive care program and screening diagnostics. In all the other cases, it’s up to us to influence the risk factors. Thereby we can reduce our own risk of developing breast cancer. It is important not only to know about breast cancer risk factors but also to realize that our health may depend on us. Of course, it is not possible to prevent breast cancer with 100% certainty. At the same time, we can reduce the risk of death through early diagnosis. Therefore, it is necessary to take into account the presence of risk factors and behave accordingly, considering your risk group. Patients’ stories So now, let’s get from theory to practice. We’ll go over two cases to illustrate how important it is to understand your risks. Subsequently, we will definitely devote a few future articles to this topic. 👉 Case 1. A 38-year-old woman with a family history of breast cancer. She didn’t have childbirth and lactation, but there is a record of pregnancy termination in her history at the age of 27. Since then, she has been constantly taking combined oral contraceptives (COCs) for contraception. 👉 Case 2. A 52-year-old woman with climacteric syndrome, type 2 diabetes, a history of 1 childbirth at 22, no lactation, 4 abortions, the last one at the age of 42. She has been taking hormone replacement therapy (HRT). So, patients already have risk factors for developing breast cancer, which they cannot change. But these women increased the risk of the disease by taking additional hormonal estrogen-containing drugs. Of course, in spite of the above cases, not everyone using HRT will develop breast cancer. However, when the disease is already there, oncologists always hear regrets about the lack of awareness. If they had known that they had been increasing the risk, they would have acted differently. Only 1 in 8 factors is enough to play a key role

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